Spravato: What to Expect | Atlanta Spravato & TMS Center

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Your Spravato® Journey in Atlanta: What to Expect Before, During, and After Treatment
At Atlanta Spravato & TMS Center, we are committed to ensuring your Spravato® (esketamine) treatment experience is safe, supportive, and well-informed. This guide outlines what you can expect during each stage of your journey, from preparation through post-treatment monitoring.

The SPRAVATO REMS Program: Ensuring Your Safety

Spravato® is only available through the FDA-mandated Risk Evaluation and Mitigation Strategy (REMS) program. This system protects patients by ensuring proper administration and post-treatment monitoring to manage potential side effects such as:
  • Sedation
  • Dissociation
  • Respiratory depression
  • Risk of abuse and misuse
REMS Requirements Include:
  • Administration only in certified healthcare settings like our Atlanta clinic
  • Self-administration under direct supervision
  • Mandatory on-site observation for a minimum of two hours post-dose
  • Spravato® is not dispensed for home use
  • Enrollment in REMS is coordinated by our team

Before Your Spravato Session

  • Medical Review: Inform your provider of all medications, supplements, and health conditions.
  • Fasting Guidelines: Avoid food for at least 2 hours and liquids for 30 minutes prior to treatment.
  • Transportation: Arrange for a ride home. Driving is not permitted until the next day.
  • Nasal Medications: Use any required nasal sprays at least one hour before the session.

During Your Spravato Session

  • Self-administer the nasal spray under direct medical supervision.
  • Relax in a quiet, supportive setting.
  • Your vital signs and mental status will be closely monitored.
  • Side effects may include dizziness, nausea, sedation, or dissociation.

Post-Treatment Monitoring

You will remain at our clinic for at least 2 hours after administration. Our clinical team will monitor for any side effects and confirm you are medically stable before discharge.

After Leaving the Clinic

You must refrain from driving, operating machinery, working, or making major decisions until the next day after a full night’s sleep. Plan for rest and low activity after treatment.

Spravato Treatment Schedule

  • Weeks 1–4: 2 sessions per week
  • Weeks 5–8: 1 session per week
  • Week 9+: 1 session weekly or biweekly, based on clinical progress

SPRAVATO withMe® Support Program

Eligible patients can access personalized support, including:
  • Insurance and benefits coordination
  • SPRAVATO® Savings Program (as little as $10 per treatment for eligible participants)
  • Rebate programs and Care Navigator support

Frequently Asked Questions

Our Trauma Service treats a wide range of traumatic experiences, including but not limited to physical or sexual assault, childhood abuse, domestic violence, accidents, natural disasters, military combat, and witnessing or experiencing violence. We provide care for both acute and chronic trauma.

Common symptoms of trauma can include flashbacks, nightmares, severe anxiety, depression, irritability, emotional numbness, difficulty concentrating, and avoidance of places or situations that trigger memories of the trauma. Physical symptoms such as headaches, fatigue, and gastrointestinal issues can also occur.

Treatments for trauma typically include therapies such as Cognitive Behavioral Therapy (CBT), Eye Movement Desensitization and Reprocessing (EMDR), trauma-focused cognitive therapy, and somatic experiencing. In some cases, medication may be prescribed to manage symptoms such as anxiety or depression. Our service also offers group therapy and support groups to provide additional support.

Evidence-based treatments for trauma, such as CBT and EMDR, have been shown to be highly effective in helping individuals process and recover from traumatic experiences. Many patients experience significant improvement in symptoms and overall quality of life. The effectiveness of treatment can depend on factors such as the individual’s commitment to therapy, the severity of the trauma, and the presence of a supportive environment.

If you are experiencing persistent symptoms that interfere with your daily life, relationships, or ability to function, it may be beneficial to seek professional help. This can include ongoing feelings of fear or helplessness, intrusive memories, avoidance behaviors, difficulty managing emotions, or physical symptoms linked to the trauma. Consulting with a mental health professional can help you determine the best course of action for your specific situation.

Ready to Start Your Spravato® Journey?

We provide a clinically safe and compassionate space for your Spravato® treatment.
 
Contact Atlanta Spravato & TMS Center today to schedule your consultation and learn if Spravato® is right for you.
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